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Department of Research and Sponsored Studies

Clinical Research for Patients

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Having a vibrant program close to home means our own doctors, nurses, and clinicians are at the heart of important clinical research designed to make lives better.

Clinical research is designed to improve the health of individuals, find better ways to treat illness, and to improve the quality of life.

Interested in Participating in Research?

Joining a research study means being at the forefront of the future of clinical care! If you’re interested in participating in a trial, please click here or email LRH_Research@mylrh.org or call 863.413.5969 to speak with a Team Member!

Current Clinical Trials

Oncology

Hollis Cancer Center Research 

Long Title: A Phase 3, Randomized Study of Adjuvant Cretostimogene Grenadenorepvec Versus Observation for the Treatment of Intermediate Risk Non-Muscle Invasive Bladder Cancer (IR-NMIBC) Following Transurethral Resection of Bladder Tumor (TURBT)

Medical Condition: Non-Muscle Invasive Bladder Cancer

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Long Title: Identification of Gaps in the Continuity of Care for Cancer Patients to Improve the Patient Experience

Medical Condition: Current or Recent Cancer Diagnosis

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Long Title: A Multi-Center Study for the Collection of Surplus Surgical Tissues for Genomics Proteomics, and Biomarker Research (Fresh, Preserved, Biofluid)

Purpose: This study aims to collect surplus surgical tissue, biofluid samples, and associated clinical data from consenting patients diagnosed with various diseases as well as healthy volunteers. These samples, including blood, urine, saliva, and tissue, will be used for research purposes, such as gene analysis, biomarker development, and diagnostic tool creation.

Goal: To improve understanding of diseases, support the development of new treatments, and contribute to future medical advancements. Donated samples may also be stored for long-term use in ongoing research.

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Long Title: Translational Medicine: Discovery and Evaluation of Biomarkers/Pharmacogenomics for the Diagnosis and Personalized Management of Patients

Purpose: This study focuses on advancing personalized therapy for diseases like cancer, autoimmune conditions, and heart disease by identifying biomarkers that can guide diagnosis and treatment. Through translational research, the study bridges basic science and clinical applications, using tissue, blood, and other biological samples to identify novel molecular changes and disease markers.

Goal: These discoveries may lead to new therapeutic targets, drug validation, and diagnostic tools that improve patient outcomes. The study also aims to develop new cell lines and assays to further investigate potential treatments.  

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Pulmonology

Lakeland Regional Health 

Long Title: A Phase III, Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Tozorakimab (MEDI3506) in Patients Hospitalized for Viral Lung Infection Requiring Supplemental Oxygen

Medical Condition: Viral Lung Infection

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Long Title:  Pulmonary Hypertension Screening in Patients with Interstitial Lung Disease for Earlier Detection

Medical Condition: Pulmonary Hypertension in Interstitial Lung Disease (PH-ILD)

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Long Title:  A Randomized, Double-blind, Parallel Group, Multi-center, Phase III Study to Assess the Efficacy of Budesonide, Glycopyrronium, and Formoterol Fumarate Metered Dose Inhaler Relative to Glycopyrronium and Formoterol Fumarate MDI on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

Medical Condition: Chronic Obstructive Pulmonary Disease (COPD)

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Infectious Disease

Lakeland Regional Health 

Long Title: RECOVER-AUTONOMIC: A Platform Protocol for Evaluation of Interventions for Autonomic Dysfunction in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Medical Condition: Long COVID

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

Long Title: RECOVER-SLEEP: A Platform Protocol for Evaluation of Interventions for Sleep Disturbances in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

Medical Condition: Long COVID

Want to learn more and see if you qualify? Please email LRH_Research@myLRH.org today. 

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Benefits of Research

Participating in a clinical research trial allows you to contribute to the advancement of medicine and help shape the future of healthcare. As a volunteer, you may gain early access to promising new treatments, receive expert medical care, and play a vital role in improving health outcomes for yourself and others. Your involvement matters — today’s breakthroughs start with participants like you.​

Frequently Asked Questions

A research study is a carefully designed investigation that helps researchers learn more about health, diseases, treatments, or behaviors. Studies can involve testing new medications, procedures, or devices—or simply observing health trends over time. The goal is to find better ways to prevent, diagnose, or treat health conditions and improve overall care.

 By joining a research study, you may:

  • Gain access to new treatments before they are widely available
  • Receive medical care and monitoring from experienced healthcare professionals
  • Play an active role in your own health journey
  • Help advance science and improve care for future patients

Your participation can make a lasting impact on medicine and public health.

Yes, there can be risks—just like with any medical procedure or treatment. These may include side effects, discomfort, or the possibility that the treatment won’t work as expected. Before you decide to join a study, the research team will explain all potential risks and benefits, so you can make an informed choice. Participation is always voluntary, and you have the right to leave a study at any time.

Your safety and rights are a top priority in any research study. Before a study begins, it goes through a strict review process to ensure it meets ethical and safety standards. During the study, trained professionals monitor your health closely, and you can ask questions or withdraw at any time. You’ll also be given an informed consent form that explains the study in detail before you agree to participate.

An Institutional Review Board (IRB) is an independent committee made up of doctors, scientists, and community members. The IRB’s job is to review and approve research studies to ensure they are ethical, safe, and respectful of participants’ rights. No study involving people can start without IRB approval.

Some studies offer compensation for your time, travel, or other expenses related to participation. The amount and type of compensation can vary depending on the study. This information will be explained to you during the consent process, so you’ll know exactly what to expect before deciding.

Interested in Participating in Research?​

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